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Home » Recipes » Easy Dinners

One Skillet Chicken Lazone

Published: Apr 19, 2022 Last Updated: Feb 3, 2023 by Marye 1317 words. | About 7 minutes to read this article.

Creamy cajun chicken lazone recipe is made in a skillet & served over pasta. This easy recipe takes under 20 minutes - perfect for busy weeknights.
Total time 18 minutes
Jump to Recipe Pin Recipe
Pasta being twirled around a fork with a title text overlay for Pinterest.

You can't go wrong with this one, y'all! This easy one skillet chicken recipe is even low carb as long as you leave off the pasta!

Overhead view of chicken in a skillet with a title text overlay.
Jump to:
  • ❤️ Why you'll love it
  • 🧾 Ingredients
  • 🔪 Instructions
  • 🥄 Equipment
  • 🥫 Storage
  • 📖 Variations
  • 💭 Things to know
  • 👩‍🍳 FAQs
  • 📚 Related recipes
  • 🍽️ Serve with...
  • 📞 The last word
  • Chicken Lazone
  • 💬 Comments

❤️ Why you'll love it

  • Simple ingredients and it takes just 15 to 20 minutes!
  • Fall apart tender chicken with spicy cajun seasoning covered in a creamy, garlicky sauce is a combination that really wakes up your tastebuds.
  • Perfect for special occasions or family dinners - and it's generally acceptable to picky eaters.

Chicken Lazone was created by Chef Lazone Randolph who was the executive chef of Brennan's restaurant in New Orleans for years. I've eaten there and let me tell you, the guy was magic with food.

Y'all, we love this stuff! It's just so darn easy and it's one of those meals that I always have the ingredients for.

If you love creamy chicken and pasta as much as I do you'll want to try this crack chicken spaghetti.

🧾 Ingredients

This is an overview of the ingredients. You'll find the full measurements and instructions in the green recipe card (printable) at the bottom of the page.

Labeled ingredients for Chicken Lazone.

The following are affiliate links. We are a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for us to earn fees by linking to Amazon.com and affiliated sites.

  • boneless skinless chicken breasts
  • heavy cream
  • butter
  • cayenne
  • chili powder
  • garlic powder
  • onion powder
  • thin spaghetti or angel hair pasta

🔪 Instructions

This is an overview of the instructions. Full instructions are in the green recipe card at the bottom of the page.

Step by step images for making this recipe.
  1. Mix the seasoning together and season the chicken with the spice mixture.
  2. Saute until golden on both sides.
  3. Add the cream and butter.
  4. Simmer until thickened, the sauce coats the back of a spoon, and chicken is cooked through. Serve over pasta, mashed potatoes, biscuits, or rice.

🥄 Equipment

The following are affiliate links. We are a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for us to earn fees by linking to Amazon.com and affiliated sites.

You'll need the following items to make this recipe successfully.

  • large skillet

🥫 Storage

We almost never have leftovers when creamy chicken lazone is on the menu!

If you happen to have some left be sure to refrigerate it promptly. Just spoon it into an airtight container or cover with plastic wrap and refrigerate for up to 4 days.

This creamy chicken recipe does not freeze well. The sauce separates and becomes watery.

A plate with chicken and pasta on it.

📖 Variations

  • Slice up smoked sausage and add it to the simmering sauce.
  • You can certainly use boneless skinless chicken thighs instead of breast.
  • You can use half and half cream instead of heavy cream and save some calories but the sauce will be watery and not as flavorful. It's not worth it, y'all.
  • I'm thinking shrimp would be delicious in this but I haven't tried it... yet.
  • Use whatever pasta you like: penne pasta, bow tie pasta (farfalle),
  • Serve over zucchini noodles (zoodles) or mashed cauliflower to make it keto.

💭 Things to know

Expert Tip: I like to season the chicken and refrigerate it overnight before cooking the next day. I think it gives it more flavor.

  • Use tenders instead of breast to make this even quicker and easier.
  • Reheat leftovers slowly over low heat or the sauce will break and get watery.
  • If you'd like a thicker sauce add a tablespoon of cornstarch to the cream before adding it to the skillet.
  • Although the delicious cream sauce cools it down, this is on the spicy side. Leave the cayenne out if you don't like the heat.
  • When the chicken is done it will register 160F on an instant read meat thermometer. It will continue to cook to 165F as it simmers in the sauce.
  • I like to sprinkle a little fresh parsley on top to make it pretty.
  • Use leftovers to make chicken spaghetti!

👩‍🍳 FAQs

What is chicken lazone?

Chicken Lazone is a creamy chicken and pasta recipe created by Chef Lazone Randolph who was the executive chef of Brennan's restaurant in New Orleans for years.

Is chicken lazone Italian?

No. It's definitely full of New Orleans flavor.

Why didn't my sauce thicken?

If you use real heavy cream that has at least 36% milk fat (read the label) AND you simmer it it will thicken. If you boil it it will break and be watery.

Pasta being twirled around a fork.

📚 Related recipes

  • Angel Chicken is very similar to this with its rich cream sauce but it isn't spicy and you make it in the slow cooker.
  • This Popeye's Blackened Chicken copycat has all that Louisiana spice, too.
  • Keto Tuscan Chicken is so tender and surrounded by a creamy, Italian sauce.
  • Try this cheesy crockpot chicken spaghetti, too.
  • Closeup of this pasta dish in a pan with a serving spoon in it.
    One Pot Chicken Alfredo with Peas
  • Closeup of the chicken broccoli casserole in the slow cooker.
    Crock Pot Broccoli Chicken Rice Casserole
  • Square feature image of chicken and noodles.
    Slow Cooker Chicken and Noodles
  • Overhead view of the finished dish for feature image.
    Baked Boneless Buffalo Chicken

🍽️ Serve with...

I love this creamy chicken lazone recipe during the week because it's so easy but if you're serving it for a company dinner your favorite cabernet sauvignon is the perfect "go with".

  • I love soft garlic breadsticks with this! They're perfect for soaking up the creamy sauce.
  • If you don't serve this with a side of pasta try these mashed potatoes.
  • Marinated green beans salad adds a tangy, crunchy flavor to the meal. I'd leave out the potatoes, though.
  • You can't go wrong with this simple buttermilk pound cake served with fresh fruit to finish the meal.

📞 The last word

Everyone needs that one great recipe that they pull out for crazy busy weeknights, unexpected visits from the in-laws, and invite-the-boss to dinner nights.

Chicken Lazone is the perfect, easy recipe. It's one of those creamy chicken recipes we all love.

If you click on the number of servings in the recipe card you can adjust the measurements up or down for the exact number of servings you need. Don't forget that you can click on "add to collection" to save it to your own, private recipe box!

If you love this recipe please give it 5 stars! ⭐️⭐️⭐️⭐️⭐️

Closeup view of this dish for feature image.
4.88 from 8 votes

Chicken Lazone

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Creamy cajun chicken lazone recipe is made in a skillet & served over pasta. This easy recipe takes under 20 minutes - perfect for busy weeknights.
Course Dinner (quick and easy)
Cuisine American - Southern
Prep Time: 5 minutes
Cook Time: 13 minutes
Total Time: 18 minutes
Servings:8
Calories:598
Author:Marye Audet-White
As an Amazon Associate I earn from qualifying purchases.

Equipment Needed

  • Iron Skillet

Ingredients

  • 2 teaspoons garlic powder
  • 1½ teaspoon chili powder
  • 1½ teaspoon onion powder
  • ½ teaspoon cayenne pepper
  • ½ teaspoon salt
  • 2 pounds boneless skinless chicken breast, chicken tenders, or thighs
  • ¼ cup butter, divided use
  • 2 cups heavy cream
  • 1 pound thin spaghetti, or your favorite pasta

I earn a commission from Instacart from qualifying purchases.

Instructions

  • Cut chicken breasts into strips.
  • Combine salt, chili powder, onion powder, garlic powder, and cayenne pepper.
  • Sprinkle over both sides of chicken.
  • Melt two tablespoons of the butter in the skillet over medium-high heat.
  • Cook the chicken until done, about 8 minutes. (165F on a meat thermometer)
  • Add the cream and remaining butter into the skillet.
  • Lower heat and simmer until the sauce thickens, about 5-7 minutes.
  • Serve chicken and sauce over thin spaghetti or your favorite pasta.
  • While the sauce is simmering cook pasta according to the instructions on the package. Drain.

Notes

Storage:
If you happen to have some left be sure to refrigerate it promptly. Just spoon it into an airtight container or cover with plastic wrap and refrigerate for up to 4 days.
This creamy chicken recipe does not freeze well. The sauce separates and becomes watery.
Tips:
Expert Tip: I like to season the chicken and refrigerate it overnight before cooking the next day. I think it gives it more flavor.
  • Use chicken tenders to make this even quicker and easier.
  • Reheat leftovers slowly over low heat or the sauce will break and get watery.
  • If you'd like a thicker sauce add a tablespoon of cornstarch to the cream before adding it to the skillet.
  • Although the delicious cream sauce cools it down, this is on the spicy side. Leave the cayenne out if you don't like the heat.
  • When the chicken is done it will register 160F on an instant read meat thermometer. It will continue to cook to 165F as it simmers in the sauce.
  • I like to sprinkle a little fresh parsley on top to make it pretty.

Nutrition Facts

Calories: 598kcal | Carbohydrates: 45g | Protein: 33g | Fat: 31g | Saturated Fat: 18g | Polyunsaturated Fat: 2g | Monounsaturated Fat: 8g | Trans Fat: 1g | Cholesterol: 155mg | Sodium: 349mg | Potassium: 627mg | Fiber: 2g | Sugar: 3g | Vitamin A: 1249IU | Vitamin C: 2mg | Calcium: 62mg | Iron: 1mg

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    About Marye

    With a 40 year focus on the importance of family and a passion for southern comfort food, Marye Audet-White is an expert in melding the two together effortlessly. Marye's a NY Times Bestselling author with 10 cookbooks under her belt and her recipes have been featured in Good Housekeeping, Country Living, Today, House Beautiful, Texas Living, Food & Wine, and many more.

    Reader Interactions

    Comments

    1. Big Johnny

      January 11, 2023 at 1:00 pm

      5 stars
      This was really good. However, I must admit that we really love spicy food, and so next time I make this, I am going to make extra of the spice mix, and add some to the cream so that the sauce will be as spicy as the wonderful chicken.

      I do have to admit, eating this made me feel like I was taking a quick trip down to New Orleans. Really yummy!

      Reply
      • Marye

        January 11, 2023 at 11:25 pm

        So glad you liked it! I add a little extra heat as well.

    2. Judy P

      September 13, 2022 at 1:28 pm

      5 stars
      I wonder how Chicken livers would taste in this? I love livers, but get tired of just frying them.

      Reply

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