Spray a 9-inch pie plate with no-stick cooking spray and set aside.
Cook the ground beef in a heavy skillet until no longer pink. Remove from heat and drain any excess fat.
Stir the frozen onion and pepper mixture, salt, garlic powder, and Worcestershire sauce into the cooked beef.
Spoon the mixture into the pie pan, spreading evenlly.
Sprinkle the cheese in an even layer over the top.
Whisk the biscuit mix, milk, and eggs together until they are smooth.
Pour over the meat mixture.
Bake for 20 - 25 minutes, or until a knife inserted in the center comes out clean.
Let cool for 5 minutes before cutting and serving.
Notes
Storage:Cover the pie dish tightly with some plastic wrap, or portion the leftovers into an airtight container. In the fridge, it'll keep for about four days.You can freeze cooked cheeseburger pie, too. Make sure it's stored tightly in a freezer-safe container, and enjoy it within three months.Tips:
Drain excess fat from ground beef after cooking.
Put the onions and peppers in frozen.
Always shred the cheese from a block - it melts better.